Fwd: Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients.

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Sat, Jun 21, 2008 at 6:01 PM
Subject: Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients.
To: mesothelioma77@gmail.com


[1]Int J Cancer. 2008 Jun 19;
Ghadersohi A, Odunsi K, Zhang S, Azrak RG, Bundy BN, Manjili MH, Li F

We have previously shown that ovarian tumors express prostate-derived Ets transcription factor (PDEF). However, the precise role of PDEF in the prognosis of ovarian cancer is unknown. In our study, we report for the first time that expression of PDEF in tumor lesions of patients with ovarian cancer is associated with favorable prognosis. Evaluation of samples from 40 patients with ovarian cancer showed that early stage (IA) and borderline (IIB, III) ovarian tumors expressed higher levels of PDEF mRNA and protein and lower levels of survivin compared to late stage ovarian tumors (IIIC and IV, p

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Source: http://www.hubmed.org/display.cgi?uids=18567002
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