Thursday, July 10, 2008

Fwd: Asbestos awareness.



Fwd: Minor Wants Out Of Prison To Care For Sick Wife (WAPT Jackson)



---------- Forwarded message ----------
From: Yahoo! News Search Results for asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 9, 2008 at 5:04 PM
Subject: Minor Wants Out Of Prison To Care For Sick Wife (WAPT Jackson)
To: mesothelioma77@gmail.com


Former attorney Paul Minor wants to be released from prison while his case is on appeal so that he can care for his sick wife.

Wed, 09 Jul 2008 18:52:28 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/asbestos+cancer/SIG=1221n6ems/*http%3A//www.wapt.com/news/16833718/detail.html?rss=jac&psp=news
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Fwd: Search the Archives (Kansas State Collegian)



---------- Forwarded message ----------
From: Yahoo! News Search Results for asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 9, 2008 at 5:04 PM
Subject: Search the Archives (Kansas State Collegian)
To: mesothelioma77@gmail.com


The temporary closure of Cardwell Hall two weeks ago to check for asbestos was just the third case of preventative measures taken against the cancer-causing substance this summer.

Wed, 09 Jul 2008 09:19:48 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/asbestos+cancer/SIG=12giafsgd/*http%3A//www.kstatecollegian.com/campus_news/asbestos_concerns_on_campus_minor
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Fwd: Minor wants out of prison to care for sick wife (The Clarion-Ledger)



---------- Forwarded message ----------
From: Yahoo! News Search Results for asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 9, 2008 at 5:04 PM
Subject: Minor wants out of prison to care for sick wife (The Clarion-Ledger)
To: mesothelioma77@gmail.com


Former attorney Paul Minor is asking a federal court to release him from prison so he can care for his sick wife during appeals of a bribery conviction that he claims was politically motivated.

Wed, 09 Jul 2008 18:45:23 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/asbestos+cancer/SIG=12inaa6cd/*http%3A//www.clarionledger.com/apps/pbcs.dll/article?AID=/20080709/NEWS/80709025
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Fwd: Asbestos Lung Cancer



Fwd: Primary pleural neoplasia: entities other than diffuse malignant mesothelioma.



---------- Forwarded message ----------
From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 9, 2008 at 5:04 PM
Subject: Primary pleural neoplasia: entities other than diffuse malignant mesothelioma.
To: mesothelioma77@gmail.com


[1]Arch Pathol Lab Med. 2008 Jul; 132(7): 1149-70
Guinee DG, Allen TC

CONTEXT: Overwhelmingly, the most common neoplasm involving the pleura is metastatic carcinoma. In contrast, diffuse malignant mesothelioma occurs relatively rarely; however, it is nonetheless the most common neoplasm primary to the pleura. Metastatic carcinoma and diffuse malignant mesothelioma each have their own prognostic and therapeutic characteristics. Other primary pleural neoplasms occur uncommonly or rarely, with their own prognostic and therapeutic characteristics. OBJECTIVE: To review primary pleural neoplasms other than diffuse malignant mesothelioma, to better ensure correct diagnosis and optimal assessment of prognosis and treatment. DATA SOURCES: Literature review and primary material from the authors' institutions. CONCLUSIONS: A nonexhaustive group of uncommon to rare benign and malignant primary pleural neoplasms--other than diffuse malignant mesothelioma--are presented, of which one must be aware in order to maintain an appropriate index of suspicion to include them in the differential diagnosis of a pleural tumor.



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Source: http://www.hubmed.org/display.cgi?uids=18605768
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Fwd: Pulmonary sarcomatous tumors.



---------- Forwarded message ----------
From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 9, 2008 at 5:04 PM
Subject: Pulmonary sarcomatous tumors.
To: mesothelioma77@gmail.com


[1]Arch Pathol Lab Med. 2008 Jul; 132(7): 1104-17
Litzky LA

CONTEXT: Sarcomatous pulmonary neoplasms are a rare and diagnostically challenging group of tumors. Primary pulmonary sarcomas must be distinguished from the more frequent occurrence of sarcoma metastatic to the lung, primary pulmonary sarcomatoid carcinoma, and diffuse malignant mesothelioma involving the lung. In current practice, the general availability of ancillary diagnostic techniques, such as immunohistochemistry and molecular analysis, can reliably classify many sarcomatoid lesions. OBJECTIVE: To review the literature and report on additional primary material about the application of immunohistochemistry and molecular analysis in the differential diagnosis pulmonary sarcomatous neoplasms. DATA SOURCES: Literature review of relevant articles indexed in PubMed (National Library of Medicine) between 1961 and 2007 and primary material from the author's institution. CONCLUSIONS: This review discusses specific criteria for the diagnosis of primary lung sarcomas and offers a practical approach to excluding other sarcoma-like lesions involving the lung. The pathologist has an essential role in evaluating these tumors and will often be the first to suggest an unusual, alternative diagnosis, which may have significant implications for patient care, therapy, and prognosis.



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Source: http://www.hubmed.org/display.cgi?uids=18605765
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Fwd: A novel combination: ranpirnase and rosiglitazone induce a synergistic apoptotic effect by down-regulating Fra-1 and Survivin in cancer cells.



---------- Forwarded message ----------
From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 9, 2008 at 5:04 PM
Subject: A novel combination: ranpirnase and rosiglitazone induce a synergistic apoptotic effect by down-regulating Fra-1 and Survivin in cancer cells.
To: mesothelioma77@gmail.com


[1]Mol Cancer Ther. 2008 Jul 7;
Ramos-Nino ME, Littenberg B

Accumulating evidence supports the idea that two known phosphatidylinositol 3'-kinase (PI3K) downstream proteins, Fra-1 and Survivin, are potential targets for cancer therapy. Increased expression of Fra-1, a Fos family member of the transcription factor activator protein-1, has been implicated in both the maintenance and the progression of the transformed state of several cancer cells. In addition, high Survivin expression in tumors correlates with more aggressive behavior, lower response to chemotherapeutic drugs, and shortened survival time. Previously, we reported that, in malignant mesothelioma cells with increased PI3K activity, small-molecule inhibitors of the PI3K/AKT pathway acted cooperatively with the amphibian RNase chemotherapeutic drug ranpirnase to inhibit cell growth. Because the thiazolidinedione antidiabetic drug rosiglitazone targets the PI3K/AKT pathway, we investigated the effect of the combination of these two drugs in cell survival in several cancer cell lines. We show here that the combination of ranpirnase and rosiglitazone synergistically decreases cell viability and increases cell apoptosis in several cancer cell lines. Cell killing is associated with decreased Fra-1 and Survivin expression and knockdown of Fra-1 increases cell killing by ranpirnase in a dose-dependent manner but not by rosiglitazone. The drug combination does not have a synergistic effect on killing in Fra-1 knockdown cells, showing that Fra-1 modulation accounts in part for the synergism. The novel drug combination of ranpirnase and rosiglitazone is a promising combination to treat cancers with increased PI3K-dependent Fra-1 expression or Survivin. [Mol Cancer Ther 2008;7(7):1871-9].



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Source: http://www.hubmed.org/display.cgi?uids=18606715
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