Fwd: EMEA Recommends Information On Lung Cancer Cases To Be Included In Exubera Product Information, Europe (Medical News Today)

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From: Yahoo! News Search Results for lung cancer <rssfwd@rssfwd.com>
Date: Fri, Jun 20, 2008 at 4:49 AM
Subject: EMEA Recommends Information On Lung Cancer Cases To Be Included In Exubera Product Information, Europe (Medical News Today)
To: mesothelioma77@gmail.com


The European Medicines Agency (EMEA) has recommended that the product information for Exubera be updated with new information on cases of lung cancer seen in patients taking the medicine. Exubera, from Pfizer Limited, is a fast-acting insulin powder for inhalation, used for the treatment of adults with type 1 or type 2 diabetes.

Wed, 18 Jun 2008 09:20:22 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/lung+cancer/SIG=11n9dg9jo/*http%3A//www.medicalnewstoday.com/articles/111649.php
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Fwd: Lung cancer radiation treatment offers new hope (Daily Telegraph)

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From: Yahoo! News Search Results for lung cancer <rssfwd@rssfwd.com>
Date: Fri, Jun 20, 2008 at 4:49 AM
Subject: Lung cancer radiation treatment offers new hope (Daily Telegraph)
To: mesothelioma77@gmail.com


Lung cancer patients with little chance of survival have been offered new hope with a treatment that targets tumours in the lungs with radiation.

Tue, 17 Jun 2008 23:10:06 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/lung+cancer/SIG=13rjj8045/*http%3A//www.telegraph.co.uk/news/newstopics/politics/health/2144985/Lung-cancer-radiation-treatment-offers-new-hope.html
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Fwd: Missouri family struggles to stay above water (Los Angeles Times)

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From: Yahoo! News Search Results for asbestos cancer <rssfwd@rssfwd.com>
Date: Sat, Jun 21, 2008 at 6:01 PM
Subject: Missouri family struggles to stay above water (Los Angeles Times)
To: mesothelioma77@gmail.com


Sat, 21 Jun 2008 04:57:27 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/asbestos+cancer/SIG=1360kmivj/*http%3A//www.latimes.com/news/nationworld/nation/la-na-victims21-2008jun21,0,2600921.story?track=rss
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Fwd: Shannon Boothe Brewer Named a Member of Cambridge Who's Who

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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Sat, Jun 21, 2008 at 6:01 PM
Subject: Shannon Boothe Brewer Named a Member of Cambridge Who's Who
To: mesothelioma77@gmail.com

Mrs. Brewer became involved in her profession because she was inspired by a compassionate and dedicated nurse who took care of her grandmother before she lost her battle to lung cancer.

Sat, 21 Jun 2008 06:00:00 GMT

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Source: http://www.24-7pressrelease.com/press-release-rss/shannon-boothe-brewer-named-a-member-of-cambridge-whos-who-54264.php
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Fwd: Expression and function of fatty acid amide hydrolase in prostate cancer.

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Sat, Jun 21, 2008 at 6:01 PM
Subject: Expression and function of fatty acid amide hydrolase in prostate cancer.
To: mesothelioma77@gmail.com


[1]Int J Cancer. 2008 Jun 19;
Endsley MP, Thill R, Choudhry I, Williams CL, Kajdacsy-Balla A, Campbell WB, Nithipatikom K

The hydrolysis of endocannabinoids has profound effects on the function of the endocannabinoid signaling system in the regulation of prostate carcinoma cells. Prostate carcinoma cells exhibit a wide range of hydrolysis activity for 2-arachidonoylglycerol (2-AG), the major endocannabinoid. However, enzyme(s) responsible for 2-AG hydrolysis and their functions in prostate cancer have not been characterized. In this study, we demonstrated that fatty acid amide hydrolase (FAAH) was differentially expressed in normal and prostate carcinoma cells. In PC-3 cells, overexpression of FAAH resulted in increased FAAH protein, 2-AG hydrolysis, cell invasion and cell migration. Conversely, small-interfering RNA (siRNA) knockdown of FAAH in LNCaP cells decreased FAAH protein, 2-AG hydrolysis and cell invasion. Furthermore, CAY10401, a FAAH inhibitor, decreased cell invasion and it enhanced the reduction of invasion in FAAH siRNA-transfected LNCaP cells. Immunohistochemistry staining of commercial tissue microarrays (TMAs) demonstrated FAAH staining in 109 of 157 cores of prostate adenocarcinomas but weak staining in 1 of 8 cores of normal prostate tissues. These results suggest that FAAH regulates 2-AG hydrolysis and invasion of prostate carcinoma cells and is potentially involved in prostate tumorigenesis. (c) 2008 Wiley-Liss, Inc.



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Source: http://www.hubmed.org/display.cgi?uids=18566995
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Fwd: Obituary: Jo Ann Gear loved to share her ceramic skill and art

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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Sat, Jun 21, 2008 at 6:01 PM
Subject: Obituary: Jo Ann Gear loved to share her ceramic skill and art
To: mesothelioma77@gmail.com

Jo Ann Gear, who operated a ceramics store and shared her craft with the community, has died at age 59.

Sat, 21 Jun 2008 07:00:00 GMT

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Source: http://www.sacbee.com/obituaries/story/1029806.html
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Fwd: Endorectal ultrasonography versus phased-array magnetic resonance imaging for preoperative staging of rectal cancer.

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Sat, Jun 21, 2008 at 6:01 PM
Subject: Endorectal ultrasonography versus phased-array magnetic resonance imaging for preoperative staging of rectal cancer.
To: mesothelioma77@gmail.com


[1]World J Gastroenterol. 2008 Jun 14; 14(22): 3504-10
Halefoglu AM, Yildirim S, Avlanmis O, Sakiz D, Baykan A

AIM: To compare the diagnostic accuracy of pelvic phased-array magnetic resonance imaging (MRI) and endorectal ultrasonography (ERUS) in the preoperative staging of rectal carcinoma. METHODS: Thirty-four patients (15 males, 19 females) with ages ranging between 29 and 75 who have biopsy proven rectal tumor underwent both MRI and ERUS examinations before surgery. All patients were evaluated to determine the diagnostic accuracy of depth of transmural tumor invasion and lymph node metastases. Imaging results were correlated with histopathological findings regarded as the gold standard and both modalities were compared in terms of predicting preoperative local staging of rectal carcinoma. RESULTS: The pathological T stage of the tumors was: pT1 in 1 patient, pT2 in 9 patients, pT3 in 21 patients and pT4 in 3 patients. The pathological N stage of the tumors was: pN0 in 19 patients, pN1 in 9 patients and pN2 in 6 patients. The accuracy of T staging for MRI was 89.70% (27 out of 34). The sensitivity was 79.41% and the specificity was 93.14%. The accuracy of T staging for ERUS was 85.29% (24 out of 34). The sensitivity was 70.59% and the specificity was 90.20%. Detection of lymph node metastases using phased-array MRI gave an accuracy of 74.50% (21 out of 34). The sensitivity and specificity was found to be 61.76% and 80.88%, respectively. By using ERUS in the detection of lymph node metastases, an accuracy of 76.47% (18 out of 34) was obtained. The sensitivity and specificity were found to be 52.94% and 84.31%, respectively. CONCLUSION: ERUS and phased-array MRI are complementary methods in the accurate preoperative staging of rectal cancer. In conclusion, we can state that phased-array MRI was observed to be slightly superior in determining the depth of transmural invasion (T stage) and has same value in detecting lymph node metastases (N stage) as compared to ERUS.



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Source: http://www.hubmed.org/display.cgi?uids=18567078
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