Fwd: The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: implications for revision of the American Joint Committee on Cancer staging system.

---------- Forwarded message ----------
From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Wed, Sep 24, 2008 at 1:30 PM
Subject: The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: implications for revision of the American Joint Committee on Cancer staging system.
To: mesothelioma77@gmail.com


[1]J Thorac Cardiovasc Surg. 2008 Sep; 136(3): 605-10
Flores RM, Routledge T, Seshan VE, Dycoco J, Zakowski M, Hirth Y, Rusch VW

OBJECTIVES: The propensity of malignant pleural mesothelioma to metastasize to N1 or N2 nodes and their corresponding prognostic value is unclear. The American Joint Committee on Cancer staging system groups N1 and N2 disease together as stage III. The goal of this study was to define the prognostic value of specific nodal stations. METHODS: Patients with malignant pleural mesothelioma who underwent resection were identified from an institutional database. Nodal stations were defined by the American Joint Committee on Cancer lung cancer node map classification. Survival was analyzed by the Kaplan-Meier method, log-rank test, and Cox proportional hazards analysis. RESULTS: From 1990 to 2006, 348 patients were identified: 279 men and 69 women with a median age of 67 years (range 26-85 years). Extrapleural pneumonectomy was performed in 223 cases, and pleurectomy/decortication was performed in 125 cases. Survival differences (P

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Fwd: George Monbiot: The patron saint of charlatans is again spreading dangerous misinformation (Guardian Unlimited)

---------- Forwarded message ----------
From: Yahoo! News Search Results for asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Sep 24, 2008 at 1:30 PM
Subject: George Monbiot: The patron saint of charlatans is again spreading dangerous misinformation (Guardian Unlimited)
To: mesothelioma77@gmail.com


George Monbiot: The Sunday Telegraph columnist Christopher Booker has published 38 articles about asbestos - and every one is wrong

Tue, 23 Sep 2008 18:47:53 GMT

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Fwd: Lung cancer mortality and iron oxide exposure in a French steel-producing factory.

---------- Forwarded message ----------
From: HubMed - asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Sep 24, 2008 at 1:31 PM
Subject: Lung cancer mortality and iron oxide exposure in a French steel-producing factory.
To: mesothelioma77@gmail.com


[1]Occup Environ Med. 2008 Sep 19;
Bourgkard E, Wild P, Courcot B, Diss M, Ettlinger J, Goutet P, Hémon D, Marquis N, Mur JM, Rigal C, Rohn-Janssens MP, Moulin JJ

OBJECTIVE: To study the possible association between iron oxide exposures and lung cancer risk among workers employed in a French steel-producing factory. METHODS: A historical cohort was set up of all workers ever employed for at least one year between 1959 and 1997. The cohort was followed up for mortality from January 1968 to December 1998. Causes of death were ascertained from death certificates. Job histories and smoking habits were available for 99.7% and 72.3% respectively. Occupational exposures were assessed by a factory-specific job-exposure matrix (JEM) developed by a panel of 8 experts and validated with atmospheric measurements. Standardized Mortality Ratios (SMRs) were computed using local death rates (external references). Poisson regressions were used to estimate the Relative Risks (RRs) for occupational exposures (internal references), adjusted on potential confounding factors. RESULTS: The cohort comprised 16,742 males and 959 females. Among males, the observed mortality was lower than expected for all causes (2,338 deaths, SMR 0.81, 0.78-0.85) and for lung cancer (233 deaths, SMR 0.89, 0.78-1.01). No lung cancer excess was observed for exposure to iron oxides (RR 0.80, 0.55-1.17) and we found no dose-response relationship with intensity, duration of exposure, and cumulative indices. Unadjusted RRs were above unity for asbestos (RR 1.14, 0.89-1.48), silica (RR 1.17, 0.76-1.80), and polycyclic aromatic hydrocarbons (RR 1.05, 0.61-1.80) compared with the non-exposed groups, and no dose-response relationship was observed with intensity, duration of exposure, and cumulative indices. A significant bladder cancer excess was observed among workers exposed to oil mist (RR 2.44, 1.06-5.60), increasing significantly with intensity, duration of exposure, and cumulative indices. CONCLUSION: This study did not detect any relationship between exposure to iron oxides and lung cancer mortality. An excess of mortality from bladder cancer was found among workers exposed to oil mist.



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Have peace of mind. Life Insurance can protect your family and love ones financially.

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